Transcriptional inhibition of miR-486-3p by BCL6 upregulates Snail and induces epithelial–mesenchymal transition during radiation-induced pulmonary fibrosis

BACKGROUND: Ionizing radiation (IR) can induce pulmonary fibrosis by causing epithelial mesenchymal transition (EMT), but the exact mechanism has not been elucidated. To investigate the molecular mechanism of how radiation induces pulmonary fibrosis by altering miR-486-3p content and thus inducing E...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Ziyan, Ao, Xingkun, Liang, Xinxin, Chen, Zhongmin, Liu, Yuhao, Wang, Ping, Wang, Duo, Liu, Zheng, Liu, Xiaochang, Zhu, Jiaojiao, Zhou, Shenghui, Zhou, Pingkun, Gu, Yongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052631/
https://www.ncbi.nlm.nih.gov/pubmed/35484551
http://dx.doi.org/10.1186/s12931-022-02024-7