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Cell surface detection of vimentin, ACE2 and SARS-CoV-2 Spike proteins reveals selective colocalization at primary cilia

The SARS-CoV-2 Spike protein mediates docking of the virus onto cells prior to viral invasion. Several cellular receptors facilitate SARS-CoV-2 Spike docking at the cell surface, of which ACE2 plays a key role in many cell types. The intermediate filament protein vimentin has been reported to be pre...

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Detalles Bibliográficos
Autores principales: Lalioti, Vasiliki, González-Sanz, Silvia, Lois-Bermejo, Irene, González-Jiménez, Patricia, Viedma-Poyatos, Álvaro, Merino, Andrea, Pajares, María A., Pérez-Sala, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052736/
https://www.ncbi.nlm.nih.gov/pubmed/35487944
http://dx.doi.org/10.1038/s41598-022-11248-y