Cargando…

Minimalist Design of an Intrinsically Disordered Protein-Mimicking Scaffold for an Artificial Membraneless Organelle

[Image: see text] Liquid–liquid phase separation (LLPS) is an emerging and universal mechanism for intracellular organization, particularly, by forming membraneless organelles (MLOs) hosting intrinsically disordered proteins (IDPs) as scaffolds. Genetic engineering is generally applied to reconstruc...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jianhui, Zhorabek, Fariza, Dai, Xin, Huang, Jinqing, Chau, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052801/
https://www.ncbi.nlm.nih.gov/pubmed/35505868
http://dx.doi.org/10.1021/acscentsci.1c01021