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Identification of novel bacterial urease inhibitors through molecular shape and structure based virtual screening approaches

The enzyme urease is an essential colonizing factor of the notorious carcinogenic pathogen Helicobacter pylori (H. pylori), conferring acid resistance to the bacterium. Recently, antibiotic resistant strains have emerged globally with little to no alternative treatment available. In this study we pr...

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Detalles Bibliográficos
Autores principales: Imran, Muhammad, Waqar, Saba, Ogata, Koji, Ahmed, Mahmood, Noreen, Zobia, Javed, Sundus, Bibi, Nazia, Bokhari, Habib, Amjad, Asma, Muddassar, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052855/
https://www.ncbi.nlm.nih.gov/pubmed/35493653
http://dx.doi.org/10.1039/d0ra02363a