Malononitrile-activated synthesis and anti-cholinesterase activity of styrylquinoxalin-2(1H)-ones

Herein, we report a base-free malononitrile activated condensation of 3-methylquinoxaline-2(1H)-one (3MQ) 1 with aryl aldehydes 3a–3ad for synthesis of styrylquinoxalin-2(1H)-ones (SQs) 4a–4ad with excellent yields. In this reaction, malononitrile activates the aldehyde via Knoevenagel condensation...

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Detalles Bibliográficos
Autores principales: Mahajan, Sheena, Slathia, Nancy, Nuthakki, Vijay K., Bharate, Sandip B., Kapoor, Kamal K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052867/
https://www.ncbi.nlm.nih.gov/pubmed/35493659
http://dx.doi.org/10.1039/d0ra02816a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052867/
https://www.ncbi.nlm.nih.gov/pubmed/35493659
http://dx.doi.org/10.1039/d0ra02816a

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