Cargando…
Malononitrile-activated synthesis and anti-cholinesterase activity of styrylquinoxalin-2(1H)-ones
Herein, we report a base-free malononitrile activated condensation of 3-methylquinoxaline-2(1H)-one (3MQ) 1 with aryl aldehydes 3a–3ad for synthesis of styrylquinoxalin-2(1H)-ones (SQs) 4a–4ad with excellent yields. In this reaction, malononitrile activates the aldehyde via Knoevenagel condensation...
Autores principales: | Mahajan, Sheena, Slathia, Nancy, Nuthakki, Vijay K., Bharate, Sandip B., Kapoor, Kamal K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052867/ https://www.ncbi.nlm.nih.gov/pubmed/35493659 http://dx.doi.org/10.1039/d0ra02816a |
Ejemplares similares
-
Methoxy-naphthyl-Linked N-Benzyl
Pyridinium Styryls as Dual Cholinesterase Inhibitors: Design, Synthesis,
Biological Evaluation, and Structure–Activity Relationship
por: Abdullaha, Mohd, et al.
Publicado: (2023) -
Discovery of Helminthosporin, an Anthraquinone Isolated
from Rumex abyssinicus Jacq as a Dual
Cholinesterase Inhibitor
por: Augustin, Ntemafack, et al.
Publicado: (2020) -
Synthesis and Biological
Evaluation of Coumarin Triazoles
as Dual Inhibitors of Cholinesterases and β-Secretase
por: Sharma, Ankita, et al.
Publicado: (2023) -
Green light triggered [2+2] cycloaddition of halochromic styrylquinoxaline—controlling photoreactivity by pH
por: Kalayci, Kubra, et al.
Publicado: (2020) -
Anti-cholinesterase activity of the standardized extract of Syzygium aromaticum L.
por: Dalai, Manoj K., et al.
Publicado: (2014)