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Cyclization step of noradrenaline and adrenaline autoxidation: a quantum chemical study

Catecholamine autoxidation has been recognized as one of the potential trigger factors for catecholaminergic neuron loss characteristics of neurodegenerative diseases. The cyclization step with intramolecular Michael addition of catecholamine o-quinones has been shown to be the irreversible and rate...

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Detalles Bibliográficos
Autor principal: Umek, Nejc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053094/
https://www.ncbi.nlm.nih.gov/pubmed/35498869
http://dx.doi.org/10.1039/d0ra02713h