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Nanocomposite liposomes for pH-controlled porphyrin release into human prostate cancer cells

It is both challenging and desirable to have drug sensitizers released at acidic tumor pH for photodynamic therapy in cancer treatment. A pH-responsive carrier was prepared, in which fumed silica-attached 5,10,15,20-tetrakis(4-trimethylammoniophenyl)porphyrin (TTMAPP) was encapsulated into 1,2-diole...

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Detalles Bibliográficos
Autores principales: Fuentes, German V., Doucet, Eric N., Abraham, Alyson, Rodgers, Nikki K., Alonso, Felix, Euceda, Nelson, Quinones, Michael H., Riascos, Penelope A., Pierre, Kristelle, Sarker, Nuhash H., Dhar-Mascareno, Manya, Cotlet, Mircea, Kisslinger, Kim, Camino, Fernando, Li, Mingxing, Lu, Fang, Gao, Ruomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053171/
https://www.ncbi.nlm.nih.gov/pubmed/35496928
http://dx.doi.org/10.1039/d0ra00846j