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Kicking KRAS to tackle lung cancer
KRAS is one of the most commonly mutated oncogenes in lung cancer but has long been considered undruggable. With the recent FDA approval of sotorasib, supported by positive phase II trial data now published in The New England Journal of Medicine, this is no longer the case.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053182/ https://www.ncbi.nlm.nih.gov/pubmed/35602221 http://dx.doi.org/10.1038/s43856-021-00017-z |