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Pan-cancer analysis of the effect of biopsy site on tumor mutational burden observations

BACKGROUND: Tumor mutational burden (TMB) has been proposed as a predictive biomarker of response to immunotherapy. Efforts to standardize TMB scores for use in the clinic and to identify the factors that could impact TMB scores are of high importance. However, the biopsy collection site has not bee...

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Detalles Bibliográficos
Autores principales: Papillon-Cavanagh, Simon, Hopkins, Julia F., Ramkissoon, Shakti H., Albacker, Lee A., Walsh, Alice M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053207/
https://www.ncbi.nlm.nih.gov/pubmed/35602225
http://dx.doi.org/10.1038/s43856-021-00054-8