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Patient-derived organoids reflect the genetic profile of endometrial tumors and predict patient prognosis

BACKGROUND: A major hurdle in translational endometrial cancer (EC) research is the lack of robust preclinical models that capture both inter- and intra-tumor heterogeneity. This has hampered the development of new treatment strategies for people with EC. METHODS: EC organoids were derived from rese...

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Detalles Bibliográficos
Autores principales: Berg, Hege F., Hjelmeland, Marta Espevold, Lien, Hilde, Espedal, Heidi, Fonnes, Tina, Srivastava, Aashish, Stokowy, Tomasz, Strand, Elin, Bozickovic, Olivera, Stefansson, Ingunn M., Bjørge, Line, Trovik, Jone, Haldorsen, Ingfrid S., Hoivik, Erling A., Krakstad, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053236/
https://www.ncbi.nlm.nih.gov/pubmed/35602206
http://dx.doi.org/10.1038/s43856-021-00019-x