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Patient-derived organoids reflect the genetic profile of endometrial tumors and predict patient prognosis
BACKGROUND: A major hurdle in translational endometrial cancer (EC) research is the lack of robust preclinical models that capture both inter- and intra-tumor heterogeneity. This has hampered the development of new treatment strategies for people with EC. METHODS: EC organoids were derived from rese...
Autores principales: | Berg, Hege F., Hjelmeland, Marta Espevold, Lien, Hilde, Espedal, Heidi, Fonnes, Tina, Srivastava, Aashish, Stokowy, Tomasz, Strand, Elin, Bozickovic, Olivera, Stefansson, Ingunn M., Bjørge, Line, Trovik, Jone, Haldorsen, Ingfrid S., Hoivik, Erling A., Krakstad, Camilla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053236/ https://www.ncbi.nlm.nih.gov/pubmed/35602206 http://dx.doi.org/10.1038/s43856-021-00019-x |
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