Spatial structure impacts adaptive therapy by shaping intra-tumoral competition

BACKGROUND: Adaptive therapy aims to tackle cancer drug resistance by leveraging resource competition between drug-sensitive and resistant cells. Here, we present a theoretical study of intra-tumoral competition during adaptive therapy, to investigate under which circumstances it will be superior to...

Descripción completa

Detalles Bibliográficos
Autores principales: Strobl, Maximilian A. R., Gallaher, Jill, West, Jeffrey, Robertson-Tessi, Mark, Maini, Philip K., Anderson, Alexander R. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053239/
https://www.ncbi.nlm.nih.gov/pubmed/35603284
http://dx.doi.org/10.1038/s43856-022-00110-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053239/
https://www.ncbi.nlm.nih.gov/pubmed/35603284
http://dx.doi.org/10.1038/s43856-022-00110-x

Ejemplares similares