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Spatial structure impacts adaptive therapy by shaping intra-tumoral competition
BACKGROUND: Adaptive therapy aims to tackle cancer drug resistance by leveraging resource competition between drug-sensitive and resistant cells. Here, we present a theoretical study of intra-tumoral competition during adaptive therapy, to investigate under which circumstances it will be superior to...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053239/ https://www.ncbi.nlm.nih.gov/pubmed/35603284 http://dx.doi.org/10.1038/s43856-022-00110-x |