Estimating heritability of glycaemic response to metformin using nationwide electronic health records and population-sized pedigree

BACKGROUND: Variability of response to medication is a well-known phenomenon, determined by both environmental and genetic factors. Understanding the heritable component of the response to medication is of great interest but challenging due to several reasons, including small study cohorts and compu...

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Detalles Bibliográficos
Autores principales: Kalka, Iris N., Gavrieli, Amir, Shilo, Smadar, Rossman, Hagai, Artzi, Nitzan Shalom, Yacovzada, Nancy-Sarah, Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053254/
https://www.ncbi.nlm.nih.gov/pubmed/35602224
http://dx.doi.org/10.1038/s43856-021-00058-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053254/
https://www.ncbi.nlm.nih.gov/pubmed/35602224
http://dx.doi.org/10.1038/s43856-021-00058-4

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