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Estimating heritability of glycaemic response to metformin using nationwide electronic health records and population-sized pedigree
BACKGROUND: Variability of response to medication is a well-known phenomenon, determined by both environmental and genetic factors. Understanding the heritable component of the response to medication is of great interest but challenging due to several reasons, including small study cohorts and compu...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053254/ https://www.ncbi.nlm.nih.gov/pubmed/35602224 http://dx.doi.org/10.1038/s43856-021-00058-4 |