Impact of azole drugs on energetics, kinetics, and ligand migration pathways of CO photo-dissociation in bacterial flavohemoglobins

Flavohemoglobins (fHbs) are heme proteins found in prokaryotic and eukaryotic microbes. They are involved in NO detoxification through an NO˙ dioxygenase mechanism. The N-terminal heme globin domain allows for binding of gaseous ligands whereas a C-terminal NADH/FADH binding domain facilitates assoc...

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Detalles Bibliográficos
Autores principales: Butcher, David, Moussaoui, Myriam, Baciou, Laura, Miksovska, Jaroslava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053618/
https://www.ncbi.nlm.nih.gov/pubmed/35515592
http://dx.doi.org/10.1039/d0ra02529a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053618/
https://www.ncbi.nlm.nih.gov/pubmed/35515592
http://dx.doi.org/10.1039/d0ra02529a

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