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Synthesis and biological evaluation of dehydroabietic acid-pyrimidine hybrids as antitumor agents

A series of novel dehydroabietic acid derivatives containing pyrimidine moieties were designed and synthesized to explore more efficacious and less toxic antitumor agents according to the principle of combination and hybridization. The cytotoxicity against human liver cancer (HepG2) cells, human bre...

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Detalles Bibliográficos
Autores principales: Huang, Lin, Huang, Rong, Pang, Fuhua, Li, Anke, Huang, Guobao, Zhou, Xiaoqun, Li, Qian, Li, Fangyao, Ma, Xianli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053630/
https://www.ncbi.nlm.nih.gov/pubmed/35517208
http://dx.doi.org/10.1039/d0ra02432e