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Synthesis and biological evaluation of dehydroabietic acid-pyrimidine hybrids as antitumor agents
A series of novel dehydroabietic acid derivatives containing pyrimidine moieties were designed and synthesized to explore more efficacious and less toxic antitumor agents according to the principle of combination and hybridization. The cytotoxicity against human liver cancer (HepG2) cells, human bre...
Autores principales: | Huang, Lin, Huang, Rong, Pang, Fuhua, Li, Anke, Huang, Guobao, Zhou, Xiaoqun, Li, Qian, Li, Fangyao, Ma, Xianli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053630/ https://www.ncbi.nlm.nih.gov/pubmed/35517208 http://dx.doi.org/10.1039/d0ra02432e |
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