The hematopoietic compartment is sufficient for lupus development resulting from the POLB-Y265C mutation

Systemic lupus erythematosus is a chronic disease characterized by autoantibodies, renal and cutaneous disease, and immune complex formation. Emerging evidence suggests that aberrant DNA repair is an underlying mechanism of lupus development. We previously showed that the POLB(Y265C/C) mutation, whi...

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Detalles Bibliográficos
Autores principales: Rahim, Tania, Levinson, Madison A., Carufe, Kelly E. W., Burak, Matthew, Meas, Rithy, Maher, Stephen, Bothwell, Alfred L. M., Gades, Naomi, Sweasy, Joann B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053796/
https://www.ncbi.nlm.nih.gov/pubmed/35486639
http://dx.doi.org/10.1371/journal.pone.0267913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053796/
https://www.ncbi.nlm.nih.gov/pubmed/35486639
http://dx.doi.org/10.1371/journal.pone.0267913

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