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A polypeptide model for toxic aberrant proteins induced by aminoglycoside antibiotics

Aminoglycoside antibiotics interfere with the selection of cognate tRNAs during translation, resulting in the synthesis of aberrant proteins that are the ultimate cause of cell death. However, the toxic potential of aberrant proteins and how they avoid degradation by the cell’s protein quality contr...

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Detalles Bibliográficos
Autores principales: Tawde, Mangala, Bior, Abdelaziz, Feiss, Michael, Teng, Feiyue, Freimuth, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053816/
https://www.ncbi.nlm.nih.gov/pubmed/35486612
http://dx.doi.org/10.1371/journal.pone.0258794