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A polypeptide model for toxic aberrant proteins induced by aminoglycoside antibiotics
Aminoglycoside antibiotics interfere with the selection of cognate tRNAs during translation, resulting in the synthesis of aberrant proteins that are the ultimate cause of cell death. However, the toxic potential of aberrant proteins and how they avoid degradation by the cell’s protein quality contr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053816/ https://www.ncbi.nlm.nih.gov/pubmed/35486612 http://dx.doi.org/10.1371/journal.pone.0258794 |