Anti-CD37 radioimmunotherapy with (177)Lu-NNV003 synergizes with the PARP inhibitor olaparib in treatment of non-Hodgkin’s lymphoma in vitro

BACKGROUND AND PURPOSE: PARP inhibitors have been shown to increase the efficacy of radiotherapy in preclinical models. Radioimmunotherapy results in selective radiation cytotoxicity of targeted tumour cells. Here we investigate the combined effect of anti-CD37 β-emitting (177)Lu-NNV003 radioimmunot...

Descripción completa

Detalles Bibliográficos
Autores principales: Malenge, Marion M., Maaland, Astri Fjelde, Repetto-Llamazares, Ada, Middleton, Brian, Nijland, Marcel, Visser, Lydia, Patzke, Sebastian, Heyerdahl, Helen, Kolstad, Arne, Stokke, Trond, Ree, Anne Hansen, Dahle, Jostein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053826/
https://www.ncbi.nlm.nih.gov/pubmed/35486574
http://dx.doi.org/10.1371/journal.pone.0267543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053826/
https://www.ncbi.nlm.nih.gov/pubmed/35486574
http://dx.doi.org/10.1371/journal.pone.0267543

Ejemplares similares