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Analytical and clinical validation of an amplicon-based next generation sequencing assay for ultrasensitive detection of circulating tumor DNA

Next-generation sequencing of circulating tumor DNA presents a promising approach to cancer diagnostics, complementing conventional tissue-based diagnostic testing by enabling minimally invasive serial testing and broad genomic coverage through a simple blood draw to maximize therapeutic benefit to...

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Detalles Bibliográficos
Autores principales: Poh, Jonathan, Ngeow, Kao Chin, Pek, Michelle, Tan, Kian-Hin, Lim, Jing Shan, Chen, Hao, Ong, Choon Kiat, Lim, Jing Quan, Lim, Soon Thye, Lim, Chwee Ming, Goh, Boon Cher, Choudhury, Yukti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053827/
https://www.ncbi.nlm.nih.gov/pubmed/35486650
http://dx.doi.org/10.1371/journal.pone.0267389