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Arrestin Facilitates Rhodopsin Dephosphorylation in Vivo

Deactivation of G-protein-coupled receptors (GPCRs) involves multiple phosphorylations followed by arrestin binding, which uncouples the GPCR from G-protein activation. Some GPCRs, such as rhodopsin, are reused many times. Arrestin dissociation and GPCR dephosphorylation are key steps in the recycli...

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Detalles Bibliográficos
Autores principales: Hsieh, Chia-Ling, Yao, Yun, Gurevich, Vsevolod V., Chen, Jeannie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053844/
https://www.ncbi.nlm.nih.gov/pubmed/35332081
http://dx.doi.org/10.1523/JNEUROSCI.0141-22.2022