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Site-specific functionalization with amino, guanidinium, and imidazolyl groups enabling the activation of 10–23 DNAzyme

10–23 DNAzyme has been extensively explored as a therapeutic and biotechnological tool, as well as in DNA computing. Faster cleavage or transformation is always needed. The present research displays a rational modification approach for a more efficient DNAzyme. In the catalytic core, amino, guanidin...

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Detalles Bibliográficos
Autores principales: Du, Shanshan, Li, Yang, Chai, Zhilong, Shi, Weiguo, He, Junlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053948/
https://www.ncbi.nlm.nih.gov/pubmed/35518333
http://dx.doi.org/10.1039/d0ra02226h