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Cascade annulation reaction (CAR): highly diastereoselective synthesis of pyranopyrazole scaffolds

An unprecedented domino protocol for the novel synthesis of highly diverse and functionalized tetrahydro pyranopyrazole scaffolds using chalcone epoxide has been reported for the first time. This synthetic protocol generates three consecutive stereogenic centres in a highly diastereoselective manner...

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Detalles Bibliográficos
Autores principales: Bakthadoss, Manickam, Surendar, Manickam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053953/
https://www.ncbi.nlm.nih.gov/pubmed/35518344
http://dx.doi.org/10.1039/d0ra03400b