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The 1α-hydroxy-A-rings of norditerpenoid alkaloids are twisted-boat conformers

The skeletal conformations of naturally occurring norditerpenoid alkaloids fix their substituent functional groups in space, thereby directing their bioactivities. Solution conformations of the A-rings of 4 selected norditerpenoid alkaloid free bases: mesaconitine, karacoline (karakoline), condelphi...

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Detalles Bibliográficos
Autores principales: Zeng, Ziyu, Qasem, Ashraf M. A., Kociok-Köhn, Gabriele, Rowan, Michael G., Blagbrough, Ian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053968/
https://www.ncbi.nlm.nih.gov/pubmed/35518334
http://dx.doi.org/10.1039/d0ra03811c