N-terminal signal peptides facilitate the engineering of PVC complex as a potent protein delivery system

Extracellular contractile injection systems (eCISs) are widespread bacterial nanomachines that resemble T4 phage tail. As a typical eCIS, Photorhabdus virulence cassette (PVC) was proposed to inject toxins into eukaryotic cells by puncturing the cell membrane from outside. This makes it an ideal too...

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Detalles Bibliográficos
Autores principales: Jiang, Feng, Shen, Jiawei, Cheng, Jiaxuan, Wang, Xia, Yang, Jianguo, Li, Ningning, Gao, Ning, Jin, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054023/
https://www.ncbi.nlm.nih.gov/pubmed/35486720
http://dx.doi.org/10.1126/sciadv.abm2343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054023/
https://www.ncbi.nlm.nih.gov/pubmed/35486720
http://dx.doi.org/10.1126/sciadv.abm2343

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