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Synthesis of tricyclic carbohydrate–benzene hybrids as selective inhibitors of galectin-1 and galectin-8 N-terminal domains

As the galactoside binding family of galectin proteins is involved in many physiological and pathological processes, the inhibitors of these proteins are considered to be of significant interest in the treatment of diseases such as cancer and fibrosis. Herein, fused tricyclic carbohydrate–benzene hy...

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Detalles Bibliográficos
Autores principales: Wu, Chunxia, Yong, Can, Zhong, Qiuju, Wang, Zhouyu, Nilsson, Ulf J., Zhang, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054096/
https://www.ncbi.nlm.nih.gov/pubmed/35515421
http://dx.doi.org/10.1039/d0ra03144e