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Synthesis of tricyclic carbohydrate–benzene hybrids as selective inhibitors of galectin-1 and galectin-8 N-terminal domains
As the galactoside binding family of galectin proteins is involved in many physiological and pathological processes, the inhibitors of these proteins are considered to be of significant interest in the treatment of diseases such as cancer and fibrosis. Herein, fused tricyclic carbohydrate–benzene hy...
Autores principales: | Wu, Chunxia, Yong, Can, Zhong, Qiuju, Wang, Zhouyu, Nilsson, Ulf J., Zhang, Yuanyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054096/ https://www.ncbi.nlm.nih.gov/pubmed/35515421 http://dx.doi.org/10.1039/d0ra03144e |
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