Synthetic and biochemical studies on the effect of persulfidation on disulfide dimer models of amyloid β42 at position 35 in Alzheimer's etiology

Protein persulfidation plays a role in redox signaling as an anti-oxidant. Dimers of amyloid β42 (Aβ42), which induces oxidative stress-associated neurotoxicity as a causative agent of Alzheimer's disease (AD), are minimum units of oligomers in AD pathology. Met35 can be susceptible to persulfi...

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Detalles Bibliográficos
Autores principales: Murakami, Kazuma, Kato, Haruka, Hanaki, Mizuho, Monobe, Yoko, Akagi, Ken-ichi, Kawase, Taiji, Hirose, Kenji, Irie, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054097/
https://www.ncbi.nlm.nih.gov/pubmed/35515472
http://dx.doi.org/10.1039/d0ra03429k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054097/
https://www.ncbi.nlm.nih.gov/pubmed/35515472
http://dx.doi.org/10.1039/d0ra03429k

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