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Estimation of a stronger heparin binding locus in fibronectin domain III(14) using thermodynamics and molecular dynamics

The HEP II (Heparin-binding site II) region of fibronectin (FN) containing domain III(14) plays a crucial role in cell adhesion and migration through heparin-binding on the cell surface. There are two such fibronectin heparin interacting peptide (FHIP I and FHIP II) sequences present in HEP II. Howe...

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Detalles Bibliográficos
Autores principales: Gupta, Sakshi, Tiwari, Neha, Verma, Jyoti, Waseem, Mohd, Subbarao, Naidu, Munde, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054198/
https://www.ncbi.nlm.nih.gov/pubmed/35520402
http://dx.doi.org/10.1039/d0ra01773f