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New synthetic procedure for the antiviral sulfonate carbosilane dendrimer G2-S16 and its fluorescein-labelled derivative for biological studies

The anionic carbosilane (CBS) dendrimer with sulfonate groups G2-S16 is a promising compound for the preparation of a microbicide gel to prevent HIV infection. However, until now its synthesis required aggressive conditions. Hence, a reliable synthetic procedure is very important to face GMP conditi...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Ulloa, Carlos, Peña-González, Cornelia E., Barrios-Gumiel, Andrea, Ceña-Díez, Rafael, Serramía-Lobera, M. Jesús, Muñoz-Fernández, M. Ángeles, Javier de la Mata, F., Sánchez-Nieves, Javier, Gómez, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054215/
https://www.ncbi.nlm.nih.gov/pubmed/35520432
http://dx.doi.org/10.1039/d0ra03448g