A novel biocompatible, simvastatin-loaded, bone-targeting lipid nanocarrier for treating osteoporosis more effectively

An insufficient drug concentration at the target site and drug efflux resulting in poor efficacy are recognized as important obstacles in osteoporosis treatment. Simvastatin (SIM), which can treat osteoporosis by promoting osteoblast differentiation and mineralization through the bone morphogenetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Tao, Shan, Chen, Shao-qing, Zhou, Wen-tao, Yu, Fang-ying, Bao, Lu, Qiu, Guo-xi, Qiao, Qing, Hu, Fu-qiang, Wang, Jian-wei, Yuan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054278/
https://www.ncbi.nlm.nih.gov/pubmed/35517758
http://dx.doi.org/10.1039/d0ra00685h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054278/
https://www.ncbi.nlm.nih.gov/pubmed/35517758
http://dx.doi.org/10.1039/d0ra00685h

Ejemplares similares