Stress stability study of simeprevir, a hepatitis C virus inhibitor, using feasible TLC-spectro-densitometry: application to pharmaceutical dosage form and human plasma

Simeprevir is one of the newest direct action anti-hepatitis C drugs. In the present work, a simple, highly selective and stability-indicating, high-performance thin-layer chromatography (HPTLC) method is proposed and validated for the assay of simeprevir both in pharmaceutical dosage form and spike...

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Detalles Bibliográficos
Autores principales: Mohammed, Bassam Shaaban, Hamad, Amal E., Derayea, Sayed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054297/
https://www.ncbi.nlm.nih.gov/pubmed/35518774
http://dx.doi.org/10.1039/d0ra01172j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054297/
https://www.ncbi.nlm.nih.gov/pubmed/35518774
http://dx.doi.org/10.1039/d0ra01172j

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