Using induced pluripotent stem cells to investigate human neuronal phenotypes in 1q21.1 deletion and duplication syndrome

Copy Number Variation (CNV) at the 1q21.1 locus is associated with a range of neurodevelopmental and psychiatric disorders in humans, including abnormalities in head size and motor deficits. Yet, the functional consequences of these CNVs (both deletion and duplication) on neuronal development remain...

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Detalles Bibliográficos
Autores principales: Chapman, Gareth, Alsaqati, Mouhamed, Lunn, Sharna, Singh, Tanya, Linden, Stefanie C., Linden, David E. J., van den Bree, Marianne B. M., Ziller, Mike, Owen, Michael J., Hall, Jeremy, Harwood, Adrian J., Syed, Yasir Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Immediate Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054650/
https://www.ncbi.nlm.nih.gov/pubmed/34112971
http://dx.doi.org/10.1038/s41380-021-01182-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054650/
https://www.ncbi.nlm.nih.gov/pubmed/34112971
http://dx.doi.org/10.1038/s41380-021-01182-2

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