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Over-representation of potential SP4 target genes within schizophrenia-risk genes
Reduction of Sp4 expression causes age-dependent hippocampal vacuolization and many other intermediate phenotypes of schizophrenia in Sp4 hypomorphic mice. Recent human genetic studies from both the Schizophrenia Exome Sequencing Meta-Analysis (SCHEMA) and the Genome-Wide Association Study (GWAS) va...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054665/ https://www.ncbi.nlm.nih.gov/pubmed/34750502 http://dx.doi.org/10.1038/s41380-021-01376-8 |