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GIPC2 interacts with Fzd7 to promote prostate cancer metastasis by activating WNT signaling

Prostate cancer (PCa) causes significant mortality and morbidity, with advanced metastasis. WNT signaling is a promising therapeutic target for metastatic PCa. GIPC2 is a GIPC1 paralog involved in WNT signaling pathways associated with tumor progression, but its role in PCa metastasis remains unclea...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Wang, Jiayi, Yin, Xiaolin, Guan, Xin, Li, Ying, Xin, Chenqi, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054671/
https://www.ncbi.nlm.nih.gov/pubmed/35347223
http://dx.doi.org/10.1038/s41388-022-02255-4