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Astrocytes in the ventral pallidum extinguish heroin seeking through GAT-3 upregulation and morphological plasticity at D1-MSN terminals

GABAergic projections from the nucleus accumbens core to the dorsolateral ventral pallidum are necessary for drug-conditioned cues to initiate relapse-like drug seeking. Astrocytes in the ventral pallidum are situated perisynaptically and regulate GABA transmission through expression of GABA uptake...

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Detalles Bibliográficos
Autores principales: Kruyer, Anna, Dixon, Danielle, Angelis, Ariana, Amato, Davide, Kalivas, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054673/
https://www.ncbi.nlm.nih.gov/pubmed/34642457
http://dx.doi.org/10.1038/s41380-021-01333-5