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Human microRNA (miR-20b-5p) modulates Alzheimer’s disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences Alzheimer’s biomarkers

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with loss of cognitive, executive, and other mental functions, and is the most common form of age-related dementia. Amyloid-β peptide (Aβ) contributes to the etiology and progression of the disease. Aβ is derived from the amyloid-β...

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Detalles Bibliográficos
Autores principales: Wang, Ruizhi, Chopra, Nipun, Nho, Kwangsik, Maloney, Bryan, Obukhov, Alexander G., Nelson, Peter T., Counts, Scott E., Lahiri, Debomoy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054681/
https://www.ncbi.nlm.nih.gov/pubmed/35087196
http://dx.doi.org/10.1038/s41380-021-01351-3