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sTREM-1 promotes the phagocytic function of microglia to induce hippocampus damage via the PI3K–AKT signaling pathway

Soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) is a soluble form of TREM-1 released during inflammation. Elevated sTREM-1 levels have been found in neuropsychiatric systemic lupus erythematosus (NPSLE) patients; yet, the exact mechanisms remain unclear. This study investigated th...

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Detalles Bibliográficos
Autores principales: Lu, Li, Liu, Xuan, Fu, Juanhua, Liang, Jun, Hou, Yayi, Dou, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054830/
https://www.ncbi.nlm.nih.gov/pubmed/35487953
http://dx.doi.org/10.1038/s41598-022-10973-8