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Computational profiling of hiPSC-derived heart organoids reveals chamber defects associated with NKX2-5 deficiency

Heart organoids have the potential to generate primary heart-like anatomical structures and hold great promise as in vitro models for cardiac disease. However, their properties have not yet been fully studied, which hinders their wide spread application. Here we report the development of differentia...

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Detalles Bibliográficos
Autores principales: Feng, Wei, Schriever, Hannah, Jiang, Shan, Bais, Abha, Wu, Haodi, Kostka, Dennis, Li, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054831/
https://www.ncbi.nlm.nih.gov/pubmed/35488063
http://dx.doi.org/10.1038/s42003-022-03346-4