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Computational profiling of hiPSC-derived heart organoids reveals chamber defects associated with NKX2-5 deficiency
Heart organoids have the potential to generate primary heart-like anatomical structures and hold great promise as in vitro models for cardiac disease. However, their properties have not yet been fully studied, which hinders their wide spread application. Here we report the development of differentia...
Autores principales: | Feng, Wei, Schriever, Hannah, Jiang, Shan, Bais, Abha, Wu, Haodi, Kostka, Dennis, Li, Guang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054831/ https://www.ncbi.nlm.nih.gov/pubmed/35488063 http://dx.doi.org/10.1038/s42003-022-03346-4 |
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