Incorporating local ancestry improves identification of ancestry-associated methylation signatures and meQTLs in African Americans

Here we report three epigenome-wide association studies (EWAS) of DNA methylation on self-reported race, global genetic ancestry, and local genetic ancestry in admixed Americans from three sets of samples, including internal and external replications (N(total )= 1224). Our EWAS on local ancestry (LA...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Boyang, Aouizerat, Bradley E., Cheng, Youshu, Anastos, Kathryn, Justice, Amy C., Zhao, Hongyu, Xu, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054854/
https://www.ncbi.nlm.nih.gov/pubmed/35488087
http://dx.doi.org/10.1038/s42003-022-03353-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054854/
https://www.ncbi.nlm.nih.gov/pubmed/35488087
http://dx.doi.org/10.1038/s42003-022-03353-5

Ejemplares similares