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Incorporating local ancestry improves identification of ancestry-associated methylation signatures and meQTLs in African Americans

Here we report three epigenome-wide association studies (EWAS) of DNA methylation on self-reported race, global genetic ancestry, and local genetic ancestry in admixed Americans from three sets of samples, including internal and external replications (N(total )= 1224). Our EWAS on local ancestry (LA...

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Detalles Bibliográficos
Autores principales:	Li, Boyang, Aouizerat, Bradley E., Cheng, Youshu, Anastos, Kathryn, Justice, Amy C., Zhao, Hongyu, Xu, Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054854/ https://www.ncbi.nlm.nih.gov/pubmed/35488087 http://dx.doi.org/10.1038/s42003-022-03353-5

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