The clinical utility of polygenic risk scores in genomic medicine practices: a systematic review

Genomic medicine aims to improve health using the individual genomic data of people to inform care. While clinical utility of genomic medicine in many monogenic, Mendelian disorders is amply demonstrated, clinical utility is less evident in polygenic traits, e.g., coronary artery disease or breast c...

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Detalles Bibliográficos
Autores principales: Kumuthini, Judit, Zick, Brittany, Balasopoulou, Angeliki, Chalikiopoulou, Constantina, Dandara, Collet, El-Kamah, Ghada, Findley, Laura, Katsila, Theodora, Li, Rongling, Maceda, Ebner Bon, Monye, Henrietta, Rada, Gabriel, Thong, Meow-Keong, Wanigasekera, Thilina, Kennel, Hannah, Marimuthu, Veeramani, Williams, Marc S., Al-Mulla, Fahd, Abramowicz, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055005/
https://www.ncbi.nlm.nih.gov/pubmed/35488921
http://dx.doi.org/10.1007/s00439-022-02452-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055005/
https://www.ncbi.nlm.nih.gov/pubmed/35488921
http://dx.doi.org/10.1007/s00439-022-02452-x

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