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Teriflunomide treatment exacerbates cardiac ischemia reperfusion injury in isolated rat hearts
PURPOSE: Previous work suggests that Dihydroorotate dehydrogenase (DHODH) inhibition via teriflunomide (TERI) may provide protection in multiple disease models. To date, little is known about the effect of TERI on the heart. This study was performed to assess the potential effects of TERI on cardiac...
Autores principales: | Alexander, Emily Davis, Aldridge, Jessa L., Burleson, T. Samuel, Frasier, Chad R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055010/ https://www.ncbi.nlm.nih.gov/pubmed/35488973 http://dx.doi.org/10.1007/s10557-022-07341-z |
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