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New chalcone derivatives: synthesis, antiviral activity and mechanism of action
In this work, twenty-eight chalcone derivatives containing a purine (sulfur) ether moiety were synthesized and their antiviral activities were evaluated. Biological results showed that compound 5d exhibited outstanding inactive activity against tobacco mosaic virus (TMV) in vivo (EC(50) = 65.8 μg mL...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055036/ https://www.ncbi.nlm.nih.gov/pubmed/35516226 http://dx.doi.org/10.1039/d0ra03684f |