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New chalcone derivatives: synthesis, antiviral activity and mechanism of action

In this work, twenty-eight chalcone derivatives containing a purine (sulfur) ether moiety were synthesized and their antiviral activities were evaluated. Biological results showed that compound 5d exhibited outstanding inactive activity against tobacco mosaic virus (TMV) in vivo (EC(50) = 65.8 μg mL...

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Detalles Bibliográficos
Autores principales:	Fu, Yun, Liu, Dan, Zeng, Huanan, Ren, Xiaoli, Song, Baoan, Hu, Deyu, Gan, Xiuhai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055036/ https://www.ncbi.nlm.nih.gov/pubmed/35516226 http://dx.doi.org/10.1039/d0ra03684f

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