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Pharmacokinetic–pharmacodynamic modeling for Moutan Cortex/Moutan Cortex charcoal and the contributions of the chemical component using support vector regression with particle swarm optimization

Moutan Cortex (MC) and Moutan Cortex charcoal (MCC) are two kinds of Chinese medicinal materials widely used in traditional Chinese medicine (TCM) with opposite drug efficacy. And the contributions of the chemical component to the drug efficacy are still not clear. In our study, a support vector reg...

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Detalles Bibliográficos
Autores principales: Pan, Sixing, Zhou, Jianan, Zhou, Sujuan, Huang, Zhangpeng, Meng, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055091/
https://www.ncbi.nlm.nih.gov/pubmed/35516193
http://dx.doi.org/10.1039/d0ra04111d